KPI-2 rabbit pAb
The protein encoded by this gene belongs to the protein kinase superfamily and the protein tyrosine kinase family. It contains N-terminal transmembrane helices and a long C-terminal cytoplasmic tail with serine/threonine/tyrosine kinase activity. This protein interacts with several other proteins, such as Inhibitor-2 (Inh2), protein phosphatase-1 (PP1C), p35, and myosin VI. It phosporylates other proteins, and is itself also phosporylated when interacting with cyclin-dependent kinase 5 (cdk5)/p35 complex. This protein involves in nerve growth factor (NGF)-TrkA signalling, and also plays a critical role in endosomal membrane trafficking. Mouse studies suggested an essential role of this protein in spermatogenesis. [provided by RefSeq, Oct 2009],
Product Specifications
Background
UniProt
Q8IWU2
Swiss Prot
Q8IWU2
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human LMTK2. AA range:651-700
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Molecular Weight
164kD
Storage Conditions
-20°C/1 year
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES5261-1.pdf
Observed Molecular Weight
164kD
Fragment
IgG
Subcellular Location
Membrane ; Multi-pass membrane protein .
Other Product Names
Gene ID (Human)
22853
Available Sizes
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