FANCG (phospho Ser383) rabbit pAb
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group G. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Synonyms
FANCG; XRCC9; Fanconi anemia group G protein; Protein FACG; DNA repair protein XRCC9
Gene ID
2189
UniProt
O15287
Cellular Locus
Nucleus. Cytoplasm. The major form is nuclear. The minor form is cytoplasmic.
Host
Rabbit
Species Reactivity
Human,Rat,Mouse,
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized phospho-peptide around the phosphorylation site of human FANCG (phospho Ser383)
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA
Validated Applications
WB,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Molecular Weight
69kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES5203-1.pdf
Observed Molecular Weight
69 kD
Subcellular Location
Nucleus . Cytoplasm . The major form is nuclear. The minor form is cytoplasmic.
Other Product Names
FANCG; XRCC9; Fanconi anemia group G protein; Protein FACG; DNA repair protein XRCC9
Gene ID (Human)
2189
SwissProt (Human)
O15287
Available Sizes
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