4.1R (phospho Tyr660) rabbit pAb
The protein encoded by this gene, together with spectrin and actin, constitute the red cell membrane cytoskeletal network. This complex plays a critical role in erythrocyte shape and deformability. Mutations in this gene are associated with type 1 elliptocytosis (EL1). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2009],
Product Specifications
Background
UniProt
P11171
Swiss Prot
P11171
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human EPB41 around the phosphorylation site of Tyr660/418. AA range:626-675
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Molecular Weight
60kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
60kD
Fragment
IgG
Subcellular Location
Cytoplasm, cytoskeleton . Cytoplasm, cell cortex . Nucleus .
Other Product Names
EPB41; E41P; Protein 4.1; P4.1; 4.1R; Band 4.1; EPB4.1
Gene ID (Human)
2035
Available Sizes
Frequently Asked Questions
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