EIF4B rabbit pAb
Function: Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F. similarity: Contains 1 RRM (RNA recognition motif) domain. subunit: Self-associates and interacts with EIF3 p170 subunit.
Product Specifications
Background
Synonyms
EIF4B; Eukaryotic translation initiation factor 4B; eIF-4B
Gene ID
1975
UniProt
P23588
Cellular Locus
Cytosol,polysome,eukaryotic translation initiation factor 4F complex,dendrite,neuronal cell body,
Host
Rabbit
Species Reactivity
Human,Mouse
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human eIF4B. AA range:388-437
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC, IF, ELISA
Validated Applications
WB,IHC,IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Molecular Weight
70kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES5075-1.pdf
Observed Molecular Weight
70 kD
Subcellular Location
Cytosol, polysome, eukaryotic translation initiation factor 4F complex, dendrite, neuronal cell body
Other Product Names
EIF4B; Eukaryotic translation initiation factor 4B; eIF-4B
Gene ID (Human)
1975
SwissProt (Human)
P23588
Available Sizes
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