Dsg2 rabbit pAb
This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10. [provided by RefSeq, Jan 2016],
Product Specifications
Background
Synonyms
DSG2; CDHF5; Desmoglein-2; Cadherin family member 5; HDGC
Gene ID
1829
UniProt
Q14126
Cellular Locus
Cell membrane ; Single-pass type I membrane protein. Cell junction, desmosome.
Host
Rabbit
Species Reactivity
Human,Rat,Mouse,
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human DSG2. AA range:401-450
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA
Validated Applications
WB,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Molecular Weight
140kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES5028-1.pdf
Observed Molecular Weight
140 kD
Subcellular Location
Cell membrane ; Single-pass type I membrane protein. Cell junction, desmosome.
Other Product Names
DSG2; CDHF5; Desmoglein-2; Cadherin family member 5; HDGC
Gene ID (Human)
1829
SwissProt (Human)
Q14126
Available Sizes
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