Cleaved-Aggrecan (D369) rabbit pAb
This gene is a member of the aggrecan/versican proteoglycan family. The encoded protein is an integral part of the extracellular matrix in cartilagenous tissue and it withstands compression in cartilage. Mutations in this gene may be involved in skeletal dysplasia and spinal degeneration. Multiple alternatively spliced transcript variants that encode different protein isoforms have been observed in this gene. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Synonyms
Gene ID
176
UniProt
P16112
Cellular Locus
Secreted, extracellular space, extracellular matrix.
Host
Rabbit
Species Reactivity
Human,Rat
Reactivity
Human; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human Aggrecan. AA range:320-369
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC, IF, ELISA
Validated Applications
WB,IHC,IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Molecular Weight
44kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES5012-1.pdf
Observed Molecular Weight
44 kD
Subcellular Location
Secreted, extracellular space, extracellular matrix .
Other Product Names
Gene ID (Human)
176
SwissProt (Human)
P16112
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
