DBH rabbit pAb

The protein encoded by this gene is an oxidoreductase belonging to the copper type II, ascorbate-dependent monooxygenase family. It is present in the synaptic vesicles of postganglionic sympathetic neurons and converts dopamine to norepinephrine. It exists in both soluble and membrane-bound forms, depending on the absence or presence, respectively, of a signal peptide. [provided by RefSeq, Jul 2008],

Product Specifications

Background

Product Name Alternative

DBH; Dopamine beta-hydroxylase; Dopamine beta-monooxygenase

UniProt

P09172

Swiss Prot

P09172

Reactivity

Human; Rat; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human DBH. AA range:401-450

Target

DBH

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Buffer

-20°C/1 year

Molecular Weight

69kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

69kD

Fragment

IgG

Subcellular Location

[Soluble dopamine beta-hydroxylase]: Cytoplasmic vesicle, secretory vesicle lumen . Cytoplasmic vesicle, secretory vesicle, chromaffin granule lumen . Secreted .; Cytoplasmic vesicle, secretory vesicle membrane ; Single-pass type II membrane protein . Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane ; Single-pass type II membrane protein .