CYP17A1 rabbit pAb
Cytochrome P450 family 17 subfamily A member 1 (CYP17A1) Homo sapiens This gene encodes a member of the Cytochrome P450 superfamily of enzymes. The Cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17, 20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17, 20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Synonyms
Gene ID
1586
UniProt
P05093
Cellular Locus
Endoplasmic reticulum membrane. Microsome membrane.
Host
Rabbit
Species Reactivity
Human
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human Cytochrome P450 17A1. AA range:221-270
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC, IF, ELISA
Validated Applications
WB,IHC,IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Molecular Weight
50kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES4948-1.pdf
Observed Molecular Weight
50 kD
Subcellular Location
Endoplasmic reticulum membrane . Microsome membrane .
Other Product Names
Gene ID (Human)
1586
SwissProt (Human)
P05093
Available Sizes
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