CYP11A1 rabbit pAb
Cytochrome P450 family 11 subfamily A member 1 (CYP11A1) Homo sapiens This gene encodes a member of the Cytochrome P450 superfamily of enzymes. The Cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Synonyms
CYP11A1; CYP11A; Cholesterol side-chain cleavage enzyme; mitochondrial; CYPXIA1; Cholesterol desmolase; Cytochrome P450 11A1; Cytochrome P450(scc)
Gene ID
1583
UniProt
P05108
Cellular Locus
Mitochondrion inner membrane ; Peripheral membrane protein. Localizes to the matrix side of the mitochondrion inner membrane..
Host
Rabbit
Species Reactivity
Human
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human Cytochrome P450 11A1. AA range:412-461
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA
Validated Applications
WB,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Molecular Weight
60kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES4947-1.pdf
Observed Molecular Weight
60 kD
Subcellular Location
Mitochondrion inner membrane ; Peripheral membrane protein . Localizes to the matrix side of the mitochondrion inner membrane. .
Other Product Names
CYP11A1; CYP11A; Cholesterol side-chain cleavage enzyme; mitochondrial; CYPXIA1; Cholesterol desmolase; Cytochrome P450 11A1; Cytochrome P450 (scc)
Gene ID (Human)
1583
SwissProt (Human)
P05108
Available Sizes
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