Pragmin (phospho Tyr413) rabbit pAb
This gene encodes an enzyme that belongs to the tyrosine protein kinase family. A similar protein in rat binds to Rho family GTPase 2 (Rnd2) and regulates neurite outgrowth via activation of Ras homolog gene family, member A (RhoA). [provided by RefSeq, Mar 2014],
Product Specifications
Background
Synonyms
SGK223; Tyrosine-protein kinase SgK223; Sugen kinase 223
Gene ID
157285
UniProt
Q86YV5
Cellular Locus
Cytoplasm. Cell junction, focal adhesion. Nucleus. Colocalized with NOTCH1 in the nucleus..
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized phospho-peptide around the phosphorylation site of human Pragmin (phospho Tyr413)
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC, IF, ELISA
Validated Applications
WB,IHC,IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight
175kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES4942-1.pdf
Observed Molecular Weight
175 kD
Subcellular Location
Cytoplasm . Cell junction, focal adhesion . Nucleus . Colocalized with NOTCH1 in the nucleus. .
Other Product Names
SGK223; Tyrosine-protein kinase SgK223; Sugen kinase 223
Gene ID (Human)
157285
SwissProt (Human)
Q86YV5
Available Sizes
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