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PP4R2 rabbit pAb

The protein encoded by this gene is a regulatory subunit of the serine/threonine-protein phosphatase 4 complex. In addition to being required for efficient DNA double strand break repair, this complex plays a role in organization of microtubules at centrosomes and processing of spliceosomal snRNPs. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015],

Product Specifications

Background

The protein encoded by this gene is a regulatory subunit of the serine/threonine-protein phosphatase 4 complex. In addition to being required for efficient DNA double strand break repair, this complex plays a role in organization of microtubules at centrosomes and processing of spliceosomal snRNPs. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]

Synonyms

PPP4R2; SBBI57; Serine/threonine-protein phosphatase 4 regulatory subunit 2

Gene ID

151987

UniProt

Q9NY27

Cellular Locus

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Ionizing radiation induces relocalization to nuclear foci and colocalization with RPA2.

Host

Rabbit

Species Reactivity

Human,Monkey

Reactivity

Human; Monkey

Immunogen

The antiserum was produced against synthesized peptide derived from human PPP4R2. AA range:171-220

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, IHC, IF, ELISA

Validated Applications

WB,IHC,IF,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

Molecular Weight

50kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES4912-1.pdf

Observed Molecular Weight

50 kD

Subcellular Location

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Ionizing radiation induces relocalization to nuclear foci and colocalization with RPA2.

Other Product Names

PPP4R2; SBBI57; Serine/threonine-protein phosphatase 4 regulatory subunit 2

Gene ID (Human)

151987

SwissProt (Human)

Q9NY27

Available Sizes

Curated Selection

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