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Eme1 rabbit pAb

This gene encodes a protein that complexes with methyl methanesulfonate-sensitive UV-sensitive 81 protein to form an endonuclease complex. The encoded protein interacts with specifc DNA structures including nicked Holliday junctions, 3'-flap structures and aberrant replication fork structures. This protein may be involved in repairing DNA damage and in maintaining genomic stability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009],

Product Specifications

Background

This gene encodes a protein that complexes with methyl methanesulfonate-sensitive UV-sensitive 81 protein to form an endonuclease complex. The encoded protein interacts with specifc DNA structures including nicked Holliday junctions, 3'-flap structures and aberrant replication fork structures. This protein may be involved in repairing DNA damage and in maintaining genomic stability. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009]

Product Name Alternative

EME1; MMS4; Crossover junction endonuclease EME1; MMS4 homolog; hMMS4

UniProt

Q96AY2

Swiss Prot

Q96AY2

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from Eme1 . at AA range: 250-330

Target

Eme1

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.

Buffer

-20°C/1 year

Molecular Weight

65kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

65kD

Fragment

IgG

Subcellular Location

Nucleus, nucleolus . Recruited to regions of DNA damage in S-phase cells.

Other Product Names

EME1; MMS4; Crossover junction endonuclease EME1; MMS4 homolog; hMMS4

Gene ID (Human)

146956

Available Sizes

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