PABP5 rabbit pAb
This gene encodes a protein that binds to the polyA tail found at the 3' end of most eukaryotic mRNAs. It is thought to play a role in the regulation of mRNA metabolic processes in the cytoplasm. This gene is located in a gene-poor region within the X-specific 13d-sY43 subinterval of the chromosome Xq21. 3/Yp11. 2 homology block. It is located close to translocation breakpoints associated with premature ovarian failure, and is therefore a potential candidate gene for this disorder. [provided by RefSeq, May 2010],
Product Specifications
Background
UniProt
Q96DU9
Swiss Prot
Q96DU9
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human PABPC5. AA range:184-233
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight
43kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
43kD
Fragment
IgG
Subcellular Location
Cytoplasm .; [Isoform 2]: Mitochondrion matrix . Co-fractionates with mtDNA and co-immunoprecipitates with the mitochondrial poly (A) polymerase.
Other Product Names
PABPC5; PABP5; Polyadenylate-binding protein 5; PABP-5; Poly (A) -binding protein 5
Gene ID (Human)
140886
Available Sizes
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