CREM rabbit pAb
CAMP responsive element modulator (CREM) Homo sapiens This gene encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Synonyms
CREM; cAMP-responsive element modulator; Inducible cAMP early repressor; ICER
Gene ID
1390
UniProt
Q03060
Cellular Locus
Nucleus.; [Isoform 6]: Cytoplasm. Nucleus.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human CREM. AA range:81-130
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC, IF, ELISA
Validated Applications
WB,IHC,IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Molecular Weight
34kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES4813-1.pdf
Observed Molecular Weight
34 kD
Subcellular Location
Nucleus.; [Isoform 6]: Cytoplasm . Nucleus .
Other Product Names
CREM; cAMP-responsive element modulator; Inducible cAMP early repressor; ICER
Gene ID (Human)
1390
SwissProt (Human)
Q03060
Available Sizes
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