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COL11A1 rabbit pAb

Collagen type XI alpha 1 chain (COL11A1) Homo sapiens This gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Mutations in this gene are associated with type II Stickler syndrome and with Marshall syndrome. A single-nucleotide polymorphism in this gene is also associated with susceptibility to lumbar disc herniation. Multiple transcript variants have been identified for this gene. [provided by RefSeq, Nov 2009],

Product Specifications

Background

Collagen type XI alpha 1 chain (COL11A1) Homo sapiens This gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Mutations in this gene are associated with type II Stickler syndrome and with Marshall syndrome. A single-nucleotide polymorphism in this gene is also associated with susceptibility to lumbar disc herniation. Multiple transcript variants have been identified for this gene. [provided by RefSeq, Nov 2009]

Product Name Alternative

COL11A1; COLL6; Collagen alpha-1 (XI) chain

UniProt

P12107

Swiss Prot

P12107

Reactivity

Human; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human Collagen XI alpha1. AA range:581-630

Target

Collagen XI α1

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. IF 1:100-300 Not yet tested in other applications.

Buffer

-20°C/1 year

Molecular Weight

181kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

181kD

Fragment

IgG

Subcellular Location

Secreted, extracellular space, extracellular matrix .

Other Product Names

COL11A1; COLL6; Collagen alpha-1 (XI) chain

Gene ID (Human)

1301

Available Sizes

Curated Selection

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