Repetin rabbit pAb

Domain: Can be divided into a N-terminal domain with significant homology to S100-like calcium-binding proteins, a central domain containing a series of short tandem repeats, and two flanking segments with low homology to the consensus sequences of the central repeats. function: Involved in the cornified cell envelope formation. Multifunctional epidermal matrix protein. Reversibly binds calcium. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. PTM: Potential substrate of transglutaminase. Some arginines are probably converted to citrullines by peptidylarginine deimidase. similarity: Belongs to the S100-fused protein family. similarity: Contains 2 EF-hand domains. tissue specificity: Expression is scattered in the normal epidermis but strong in the acrosyringium, the inner hair root sheat and in the filiform papilli of the tongue.