CKR-4 rabbit pAb
The protein encoded by this gene belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Synonyms
CCR4; CMKBR4; C-C chemokine receptor type 4; C-C CKR-4; CC-CKR-4; CCR-4; CCR4; K5-5; CD antigen CD194
Gene ID
1233
UniProt
P51679
Cellular Locus
Cell membrane; Multi-pass membrane protein.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human CCR4. AA range:211-260
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
IF, ELISA
Validated Applications
IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Molecular Weight
41kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES4707-1.pdf
Observed Molecular Weight
41 kD
Subcellular Location
Cell membrane; Multi-pass membrane protein.
Other Product Names
CCR4; CMKBR4; C-C chemokine receptor type 4; C-C CKR-4; CC-CKR-4; CCR-4; CCR4; K5-5; CD antigen CD194
Gene ID (Human)
1233
SwissProt (Human)
P51679
Available Sizes
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