TPH2 rabbit pAb
This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression. [provided by RefSeq, Feb 2016],
Product Specifications
Background
Product Name Alternative
TPH2; NTPH; Tryptophan 5-hydroxylase 2; Neuronal tryptophan hydroxylase; Tryptophan 5-monooxygenase 2
UniProt
Q8IWU9
Swiss Prot
Q8IWU9
Reactivity
Human; Mouse; Rat; Monkey
Immunogen
The antiserum was produced against synthesized peptide derived from human TPH2. AA range:4-53
Target
TPH2
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
56kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
56kD
Fragment
IgG
Subcellular Location
Cytosol, neuron projection
Other Product Names
TPH2; NTPH; Tryptophan 5-hydroxylase 2; Neuronal tryptophan hydroxylase; Tryptophan 5-monooxygenase 2
Gene ID (Human)
121278
Available Sizes
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