IKKα/β (phospho Ser176/177) rabbit pAb
This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq, Jul 2008],
Product Specifications
Background
UniProt
O15111/O14920
Swiss Prot
O15111/O14920
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human IKK-alpha around the phosphorylation site of Ser177. AA range:151-200
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight
80kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
80kD
Fragment
IgG
Subcellular Location
Cytoplasm . Nucleus . Shuttles between the cytoplasm and the nucleus.
Other Product Names
Gene ID (Human)
1147/3551
Available Sizes
Frequently Asked Questions
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