VPS26B rabbit pAb

Function: Probable component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. similarity: Belongs to the VPS26 family. subcellular location: Does not localize to endosomes. subunit: Probable component of the retromer complex composed of VPS26 (VPS26A or VPS26B), VPS29, VPS35, SNX1 and SNX2. Interacts directly with VPS35.

Product Specifications

Background

Function:Probable component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the VPS26 family., subcellular location:Does not localize to endosomes., subunit:Probable component of the retromer complex composed of VPS26 (VPS26A or VPS26B), VPS29, VPS35, SNX1 and SNX2. Interacts directly with VPS35.

Product Name Alternative

VPS26B; Vacuolar protein sorting-associated protein 26B; Vesicle protein sorting 26B

UniProt

Q4G0F5

Swiss Prot

Q4G0F5

Reactivity

Human; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human VPS26B. AA range:231-280

Target

VPS26B

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Buffer

-20°C/1 year

Molecular Weight

45kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

45kD

Fragment

IgG

Subcellular Location

Cytoplasm . Membrane; Peripheral membrane protein . Early endosome . Late endosome . Localizes to early and late endosomal structures (By similarity) . .