Ataxin-2L rabbit pAb

This gene encodes an ataxin type 2 related protein of unknown function. This protein is a member of the spinocerebellar ataxia (SCAs) family, which is associated with a complex group of neurodegenerative disorders. Several alternatively spliced transcripts encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Product Specifications

Background

Product Name Alternative

ATXN2L; A2D; A2LG; A2LP; A2RP; Ataxin-2-like protein; Ataxin-2 domain protein; Ataxin-2-related protein

UniProt

Q8WWM7

Swiss Prot

Q8WWM7

Reactivity

Human; Rat; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human ATXN2L. AA range:571-620

Target

Ataxin-2L

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Buffer

-20°C/1 year

Molecular Weight

113kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

113kD

Fragment

IgG

Subcellular Location

Membrane ; Peripheral membrane protein . Cytoplasm . Nucleus speckle . Cytoplasmic granule . Predominantly cytoplasmic but is also detected in nuclear speckles (PubMed:23209657) . Component of cytoplasmic stress granules (PubMed:23209657) . Inhibition of methylation alters nuclear localization (PubMed:25748791) . Methylation does not seem to be required for localization to stress granules under stress conditions (PubMed:25748791) . .