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OGFR rabbit pAb

The protein encoded by this gene is a receptor for opioid growth factor (OGF), also known as [Met (5)]-enkephalin. OGF is a negative regulator of cell proliferation and tissue organization in a variety of processes. The encoded unbound receptor for OGF has been localized to the outer nuclear envelope, where it binds OGF and is translocated into the nucleus. The coding sequence of this gene contains a polymorphic region of 60 nt tandem imperfect repeat units. Several transcripts containing between zero and eight repeat units have been reported. [provided by RefSeq, Jul 2008],

Product Specifications

Background

The protein encoded by this gene is a receptor for opioid growth factor (OGF), also known as [Met (5) ]-enkephalin. OGF is a negative regulator of cell proliferation and tissue organization in a variety of processes. The encoded unbound receptor for OGF has been localized to the outer nuclear envelope, where it binds OGF and is translocated into the nucleus. The coding sequence of this gene contains a polymorphic region of 60 nt tandem imperfect repeat units. Several transcripts containing between zero and eight repeat units have been reported. [provided by RefSeq, Jul 2008]

Synonyms

OGFR; Opioid growth factor receptor; OGFr; Protein 7-60; Zeta-type opioid receptor

Gene ID

11054

UniProt

Q9NZT2

Cellular Locus

Cytoplasm. Nucleus. The OGF/OGFR complex is probably translocated to the nucleus.

Host

Rabbit

Species Reactivity

Human

Reactivity

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human OGFR. AA range:138-187

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, ELISA

Validated Applications

WB,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Molecular Weight

90kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES4587-1.pdf

Observed Molecular Weight

90 kD

Subcellular Location

Cytoplasm . Nucleus . The OGF/OGFR complex is probably translocated to the nucleus.

Other Product Names

OGFR; Opioid growth factor receptor; OGFr; Protein 7-60; Zeta-type opioid receptor

Gene ID (Human)

11054

SwissProt (Human)

Q9NZT2

Available Sizes

Curated Selection

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