NFAT5 (phospho Ser1197) rabbit pAb

The product of this gene is a member of the nuclear factors of activated T cells family of transcription factors. Proteins belonging to this family play a central role in inducible gene transcription during the immune response. This protein regulates gene expression induced by osmotic stress in mammalian cells. Unlike monomeric members of this protein family, this protein exists as a homodimer and forms stable dimers with DNA elements. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Product Specifications

Background

UniProt

O94916

Swiss Prot

O94916

Reactivity

Human; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human NFAT5 around the phosphorylation site of Ser1197. AA range:1171-1220

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC

Concentration

1 mg/ml

Dilution

WB 1:500-2000; IHC-p 1:50-300

Storage Conditions

-20°C/1 year

Fragment

IgG

Subcellular Location

Nucleus . Cytoplasm . Nuclear distribution increases under hypertonic conditions. .

Other Product Names

NFAT5; KIAA0827; TONEBP; Nuclear factor of activated T-cells 5; NF-AT5; T-cell transcription factor NFAT5; Tonicity-responsive enhancer-binding protein; TonE-binding protein; TonEBP