DL-threo-3-Hydroxyaspartic acid
DL-threo-3-Hydroxyaspartic acid is a glutamate uptake inhibitor that can block glutamate transport in cannulated sprague dawley rat[1][2].
Product Specifications
CAS Number
4294-45-5
UNSPSC
12352209
Hazard Statement
H302, H315, H319, H335
Target
IGluR
Type
Peptides
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/dl-threo-3-hydroxyaspartic-acid.html
Purity
99.81
Solubility
H2O : 16.67 mg/mL (ultrasonic; adjust pH to 12 with 1 M NaOH)
Smiles
OC([C@@H](O)[C@H](N)C(O)=O)=O
Molecular Formula
C4H7NO5
Molecular Weight
149.10
Precautions
H302, H315, H319, H335
References & Citations
[1]A Klegeris, et al. Regulation of glutamate in cultures of human monocytic THP-1 and astrocytoma U-373 MG cells.J Neuroimmunol.1997 Sep;78 (1-2) :152-61.|[2]Jessica Darman, et al. Viral-induced spinal motor neuron death is non-cell-autonomous and involves glutamate excitotoxicity.J Neurosci. 2004 Aug 25;24 (34) :7566-75.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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