NHE-6 rabbit pAb

This gene encodes a sodium-hydrogen exchanger that is amember of the solute carrier family 9. The encoded protein localizes to early and recycling endosomes and may be involved in regulating endosomal pH and volume. Defects in this gene are associated with X-linked syndromic mental retardation, Christianson type. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010],

Product Specifications

Background

Product Name Alternative

SLC9A6; KIAA0267; NHE6; Sodium/hydrogen exchanger 6; Na (+) /H (+) exchanger 6; NHE-6; Solute carrier family 9 member 6

UniProt

Q92581

Swiss Prot

Q92581

Reactivity

Human; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human SLC9A6. AA range:551-600

Target

NHE-6

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

Buffer

-20°C/1 year

Molecular Weight

75kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

75kD

Fragment

IgG

Subcellular Location

Endosome membrane ; Multi-pass membrane protein . Is present in the recycling compartments including early and recycling endosomes, and only appears transiently on the plasma membrane.; [Isoform 2]: Recycling endosome membrane ; Multi-pass membrane protein .