Cdc42EP2 rabbit pAb
CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of CDC42. Coexpression of this protein with CDC42 suggested a role of this protein in actin filament assembly and cell shape control. [provided by RefSeq, Aug 2011],
Product Specifications
Background
Synonyms
CDC42EP2; BORG1; CEP2; Cdc42 effector protein 2; Binder of Rho GTPases 1
Gene ID
10435
UniProt
O14613
Cellular Locus
Endomembrane system ; Peripheral membrane protein. Cytoplasm, cytoskeleton.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human BORG1. AA range:10-59
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC, IF, ELISA
Validated Applications
WB,IHC,IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Molecular Weight
28kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES4471-1.pdf
Observed Molecular Weight
28 kD
Subcellular Location
Endomembrane system ; Peripheral membrane protein . Cytoplasm, cytoskeleton .
Other Product Names
CDC42EP2; BORG1; CEP2; Cdc42 effector protein 2; Binder of Rho GTPases 1
Gene ID (Human)
10435
SwissProt (Human)
O14613
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
Recombinant Callithrix jacchus Protein SFI1 homolog (SFI1), partial
Recombinant Callithrix jacchus Protein SFI1 homolog (SFI1), partial
Recombinant Callithrix jacchus Protein SFI1 homolog (SFI1), partial
Recombinant Callithrix jacchus Protein SFI1 homolog (SFI1), partial
