Cdc42EP2 rabbit pAb
CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of CDC42. Coexpression of this protein with CDC42 suggested a role of this protein in actin filament assembly and cell shape control. [provided by RefSeq, Aug 2011],
Product Specifications
Background
Synonyms
CDC42EP2; BORG1; CEP2; Cdc42 effector protein 2; Binder of Rho GTPases 1
Gene ID
10435
UniProt
O14613
Cellular Locus
Endomembrane system ; Peripheral membrane protein. Cytoplasm, cytoskeleton.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human BORG1. AA range:10-59
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC, IF, ELISA
Validated Applications
WB,IHC,IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Molecular Weight
28kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES4471-1.pdf
Observed Molecular Weight
28 kD
Subcellular Location
Endomembrane system ; Peripheral membrane protein . Cytoplasm, cytoskeleton .
Other Product Names
CDC42EP2; BORG1; CEP2; Cdc42 effector protein 2; Binder of Rho GTPases 1
Gene ID (Human)
10435
SwissProt (Human)
O14613
Available Sizes
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