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Epac rabbit pAb

Caution: It is uncertain whether Met-1 or Met-43 is the initiator. Domain: The DEP domain is involved in membrane localization independent from regulation by cAMP. function: Guanine nucleotide exchange factor (GEF) for RAP1A and RAP2A small GTPases that is activated by binding cAMP. similarity: Contains 1 cyclic nucleotide-binding domain. similarity: Contains 1 DEP domain. similarity: Contains 1 N-terminal Ras-GEF domain. similarity: Contains 1 Ras-GEF domain. tissue specificity: Widely expressed with highest levels in adult kidney, heart, thyroid and brain, and fetal kidney.

Product Specifications

Background

Caution:It is uncertain whether Met-1 or Met-43 is the initiator., domain:The DEP domain is involved in membrane localization independent from regulation by cAMP., function:Guanine nucleotide exchange factor (GEF) for RAP1A and RAP2A small GTPases that is activated by binding cAMP., similarity:Contains 1 cyclic nucleotide-binding domain., similarity:Contains 1 DEP domain., similarity:Contains 1 N-terminal Ras-GEF domain., similarity:Contains 1 Ras-GEF domain., tissue specificity:Widely expressed with highest levels in adult kidney, heart, thyroid and brain, and fetal kidney.

Product Name Alternative

RAPGEF3; CGEF1; EPAC; EPAC1; Rap guanine nucleotide exchange factor 3; Exchange factor directly activated by cAMP 1; Exchange protein directly activated by cAMP 1; EPAC 1; Rap1 guanine-nucleotide-exchange factor directly activated by cAMP

UniProt

O95398

Swiss Prot

O95398

Reactivity

Human; Mouse; Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human RAPGEF3. AA range:712-761

Target

Epac

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

Buffer

-20°C/1 year

Molecular Weight

100kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

100kD

Fragment

IgG

Subcellular Location

Endomembrane system .

Other Product Names

RAPGEF3; CGEF1; EPAC; EPAC1; Rap guanine nucleotide exchange factor 3; Exchange factor directly activated by cAMP 1; Exchange protein directly activated by cAMP 1; EPAC 1; Rap1 guanine-nucleotide-exchange factor directly activated by cAMP

Gene ID (Human)

10411

Available Sizes

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