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NMUR1 rabbit pAb

Caution: It is uncertain whether Met-1 or Met-24 is the initiator. function: Receptor for the neuromedin-U and neuromedin-S neuropeptides. similarity: Belongs to the G-protein coupled receptor 1 family. tissue specificity: Expressed in greatest abundance in peripheral organs, particularly in elements of the gastrointestinal and urogenital systems with highest levels in testes. In central nervous system structures express levels are much lower than those seen in peripheral organs. Within the CNS, has been detected in highest abundance in the cerebellum, dorsal root ganglia, hippocampus, and spinal cord.

Product Specifications

Background

Caution:It is uncertain whether Met-1 or Met-24 is the initiator., function:Receptor for the neuromedin-U and neuromedin-S neuropeptides., similarity:Belongs to the G-protein coupled receptor 1 family., tissue specificity:Expressed in greatest abundance in peripheral organs, particularly in elements of the gastrointestinal and urogenital systems with highest levels in testes. In central nervous system structures express levels are much lower than those seen in peripheral organs. Within the CNS, has been detected in highest abundance in the cerebellum, dorsal root ganglia, hippocampus, and spinal cord.

Synonyms

NMUR1; GPR66; Neuromedin-U receptor 1; NMU-R1; G-protein coupled receptor 66; G-protein coupled receptor FM-3

Gene ID

10316

UniProt

Q9HB89

Cellular Locus

Cell membrane; Multi-pass membrane protein.

Host

Rabbit

Species Reactivity

Human,Rat,Mouse,

Reactivity

Human; Rat; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human NMUR1. AA range:1-50

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, IF, ELISA

Validated Applications

WB,IF,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

Molecular Weight

48kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES4461-1.pdf

Observed Molecular Weight

48 kD

Subcellular Location

Cell membrane; Multi-pass membrane protein.

Other Product Names

NMUR1; GPR66; Neuromedin-U receptor 1; NMU-R1; G-protein coupled receptor 66; G-protein coupled receptor FM-3

Gene ID (Human)

10316

SwissProt (Human)

Q9HB89

Available Sizes

Curated Selection

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