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DEF-3 rabbit pAb

Disease: Defects in RBM6 are found in non-small cell lung cancer (NSCLC) cell lines. function: Specifically binds poly (G) RNA homopolymers in vitro. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. similarity: Contains 1 G-patch domain. similarity: Contains 1 RRM (RNA recognition motif) domain. tissue specificity: Ubiquitous in adults.

Product Specifications

Background

Disease:Defects in RBM6 are found in non-small cell lung cancer (NSCLC) cell lines., function:Specifically binds poly (G) RNA homopolymers in vitro., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Contains 1 G-patch domain., similarity:Contains 1 RRM (RNA recognition motif) domain., tissue specificity:Ubiquitous in adults.

UniProt

P78332

Swiss Prot

P78332

Reactivity

Human; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human RBM6. AA range:991-1040

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Molecular Weight

150kD

Storage Conditions

-20°C/1 year

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES4433-1.pdf

Observed Molecular Weight

150kD

Fragment

IgG

Subcellular Location

Nucleus .

Other Product Names

RBM6; DEF3; RNA-binding protein 6; Lung cancer antigen NY-LU-12; Protein G16; RNA-binding motif protein 6; RNA-binding protein DEF-3

Gene ID (Human)

10180

Available Sizes

Curated Selection

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