DEF-3 rabbit pAb
Disease: Defects in RBM6 are found in non-small cell lung cancer (NSCLC) cell lines. function: Specifically binds poly (G) RNA homopolymers in vitro. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. similarity: Contains 1 G-patch domain. similarity: Contains 1 RRM (RNA recognition motif) domain. tissue specificity: Ubiquitous in adults.
Product Specifications
Background
Synonyms
RBM6; DEF3; RNA-binding protein 6; Lung cancer antigen NY-LU-12; Protein G16; RNA-binding motif protein 6; RNA-binding protein DEF-3
Gene ID
10180
UniProt
P78332
Cellular Locus
Nucleus.
Host
Rabbit
Species Reactivity
Human,Mouse
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human RBM6. AA range:991-1040
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC, IF, ELISA
Validated Applications
WB,IHC,IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Molecular Weight
150kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES4433-1.pdf
Observed Molecular Weight
150 kD
Subcellular Location
Nucleus .
Other Product Names
RBM6; DEF3; RNA-binding protein 6; Lung cancer antigen NY-LU-12; Protein G16; RNA-binding motif protein 6; RNA-binding protein DEF-3
Gene ID (Human)
10180
SwissProt (Human)
P78332
Available Sizes
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