OB-cadherin rabbit pAb
This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Product Name Alternative
CDH11; Cadherin-11; OSF-4; Osteoblast cadherin; OB-cadherin
UniProt
P55287
Swiss Prot
P55287
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human CDH11. AA range:421-470
Target
OB-cadherin
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
85kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
85kD
Fragment
IgG
Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Other Product Names
CDH11; Cadherin-11; OSF-4; Osteoblast cadherin; OB-cadherin
Gene ID (Human)
1009
Available Sizes
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