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AChRα1 rabbit pAb

The muscle acetylcholine receptor consiststs of 5 subunits of 4 different types: 2 alpha subunits and 1 each of the beta, gamma, and delta subunits. This gene encodes an alpha subunit that plays a role in acetlycholine binding/channel gating. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Nov 2012],

Product Specifications

Background

The muscle acetylcholine receptor consiststs of 5 subunits of 4 different types: 2 alpha subunits and 1 each of the beta, gamma, and delta subunits. This gene encodes an alpha subunit that plays a role in acetlycholine binding/channel gating. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Nov 2012]

Synonyms

CHRNA1; ACHRA; CHNRA; Acetylcholine receptor subunit alpha

Gene ID

1134

UniProt

P02708

Cellular Locus

Cell junction, synapse, postsynaptic cell membrane ; Multi-pass membrane protein. Cell membrane ; Multi-pass membrane protein.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Reactivity

Human; Mouse; Rat

Immunogen

The antiserum was produced against synthesized peptide derived from the Internal region of human CHRNA1. AA range:171-220

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, IF, ELISA

Validated Applications

WB,IF,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

Western Blot: 1/500 - 1/2000. ELISA: 1/5000. IF 1:100-300 Not yet tested in other applications.

Molecular Weight

55kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES4285-1.pdf

Observed Molecular Weight

55 kD

Subcellular Location

Cell junction, synapse, postsynaptic cell membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein .

Other Product Names

CHRNA1; ACHRA; CHNRA; Acetylcholine receptor subunit alpha

Gene ID (Human)

1134

SwissProt (Human)

P02708

Available Sizes

Curated Selection

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