Rutaecarpine
Rutaecarpine, an alkaloid of Evodia rutaecarpa, is an inhibitor of COX-2 with an IC50 value of 0.28 μM.
Product Specifications
CAS Number
[84-26-4]
Product Name Alternative
Rutecarpine
UNSPSC
12352005
Hazard Statement
H301+H311+H331
Target
COX
Type
Natural Products
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cancer
Assay Protocol
https://www.medchemexpress.com/Rutaecarpine.html
Purity
99.09
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C1N2C(C(NC3=C4C=CC=C3)=C4CC2)=NC5=C1C=CC=C5
Molecular Formula
C18H13N3O
Molecular Weight
287.32
Precautions
P264-P270-P330-P405-P501
References & Citations
[1]Moon TC, et al. A new class of COX-2 inhibitor, rutaecarpine from Evodia rutaecarpa. Inflamm Res. 1999 Dec;48 (12) :621-5.|[2]Lee SH, et al. Progress in the studies on rutaecarpine. Molecules. 2008 Feb 6;13 (2) :272-300.|[3]Jeon TW, et al. Immunosuppressive effects of rutaecarpine in female BALB/c mice.
 Toxicol Lett. 2006 Jul 1;164 (2) :155-66.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
COX-1; COX-2
Available Sizes
Curated Selection
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