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ALR rabbit pAb

The hepatotrophic factor designated augmenter of liver regeneration (ALR) is thought to be one of the factors responsible for the extraordinary regenerative capacity of mammalian liver. It has also been called hepatic regenerative stimulation substance (HSS). The gene resides on chromosome 16 in the interval containing the locus for polycystic kidney disease (PKD1). The putative gene product is 42% similar to the scERV1 protein of yeast. The yeast scERV1 gene had been found to be essential for oxidative phosphorylation, the maintenance of mitochondrial genomes, and the cell division cycle. The human gene is both the structural and functional homolog of the yeast scERV1 gene. [provided by RefSeq, Jul 2008],

Product Specifications

Background

The hepatotrophic factor designated augmenter of liver regeneration (ALR) is thought to be one of the factors responsible for the extraordinary regenerative capacity of mammalian liver. It has also been called hepatic regenerative stimulation substance (HSS) . The gene resides on chromosome 16 in the interval containing the locus for polycystic kidney disease (PKD1) . The putative gene product is 42% similar to the scERV1 protein of yeast. The yeast scERV1 gene had been found to be essential for oxidative phosphorylation, the maintenance of mitochondrial genomes, and the cell division cycle. The human gene is both the structural and functional homolog of the yeast scERV1 gene. [provided by RefSeq, Jul 2008]

Product Name Alternative

GFER; ALR; HERV1; HPO; FAD-linked sulfhydryl oxidase ALR; Augmenter of liver regeneration; hERV1; Hepatopoietin

UniProt

P55789

Swiss Prot

P55789

Reactivity

Human; Mouse; Rat

Immunogen

The antiserum was produced against synthesized peptide derived from the Internal region of human GFER. AA range:51-100

Target

ALR

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/20000. Not yet tested in other applications.

Buffer

-20°C/1 year

Molecular Weight

24kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

24kD

Fragment

IgG

Subcellular Location

[Isoform 1]: Mitochondrion intermembrane space. Mitochondrion .; [Isoform 2]: Cytoplasm. Secreted.

Other Product Names

GFER; ALR; HERV1; HPO; FAD-linked sulfhydryl oxidase ALR; Augmenter of liver regeneration; hERV1; Hepatopoietin

Gene ID (Human)

2671

Available Sizes

Curated Selection

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