SAMHD1 rabbit pAb
SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 (SAMHD1) Homo sapiens This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome. [provided by RefSeq, Mar 2010],
Product Specifications
Background
Synonyms
SAMHD1; MOP5; SAM domain and HD domain-containing protein 1; Dendritic cell-derived IFNG-induced protein; DCIP; Monocyte protein 5; MOP-5
Gene ID
25939
UniProt
Q9Y3Z3
Cellular Locus
Nucleus. Chromosome. Localizes to sites of DNA double-strand breaks in response to DNA damage..
Host
Rabbit
Species Reactivity
Human,Rat,Mouse,
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human SAMHD1. AA range:431-480
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC, IF, ELISA
Validated Applications
WB,IHC,IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Molecular Weight
72kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES4221-1.pdf
Observed Molecular Weight
72 kD
Subcellular Location
Nucleus . Chromosome . Localizes to sites of DNA double-strand breaks in response to DNA damage. .
Other Product Names
SAMHD1; MOP5; SAM domain and HD domain-containing protein 1; Dendritic cell-derived IFNG-induced protein; DCIP; Monocyte protein 5; MOP-5
Gene ID (Human)
25939
SwissProt (Human)
Q9Y3Z3
Available Sizes
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