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NKp44 rabbit pAb

Function: Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. similarity: Belongs to the natural cytotoxicity receptor (NCR) family. similarity: Contains 1 Ig-like (immunoglobulin-like) domain. subunit: Interacts with TYROBP/DAP12. tissue specificity: Selectively expressed by activated NK cells and by in vitro cultured (i. e. activated) TCRg/d lymphoid cells.

Product Specifications

Background

Function:Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis., similarity:Belongs to the natural cytotoxicity receptor (NCR) family., similarity:Contains 1 Ig-like (immunoglobulin-like) domain., subunit:Interacts with TYROBP/DAP12., tissue specificity:Selectively expressed by activated NK cells and by in vitro cultured (i.e. activated) TCRg/d lymphoid cells.

Synonyms

NCR2; LY95; Natural cytotoxicity triggering receptor 2; Lymphocyte antigen 95 homolog; NK cell-activating receptor; Natural killer cell p44-related protein; NK-p44; NKp44; CD336

Gene ID

9436

UniProt

O95944

Cellular Locus

Cell membrane ; Single-pass type I membrane protein.

Host

Rabbit

Species Reactivity

Human,Rat,Mouse,

Reactivity

Human; Rat; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from the Internal region of human NCR2. AA range:61-110

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, IHC, IF, ELISA

Validated Applications

WB,IHC,IF,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.

Molecular Weight

44kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES4211-1.pdf

Observed Molecular Weight

44 kD

Subcellular Location

Cell membrane ; Single-pass type I membrane protein .

Other Product Names

NCR2; LY95; Natural cytotoxicity triggering receptor 2; Lymphocyte antigen 95 homolog; NK cell-activating receptor; Natural killer cell p44-related protein; NK-p44; NKp44; CD336

Gene ID (Human)

9436

SwissProt (Human)

O95944

Available Sizes

Curated Selection

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