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EKLF rabbit pAb

This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In (Lu) blood phenotype. [provided by RefSeq, Oct 2009],

Product Specifications

Background

This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In (Lu) blood phenotype. [provided by RefSeq, Oct 2009]

Product Name Alternative

KLF1; EKLF; Krueppel-like factor 1; Erythroid krueppel-like transcription factor; EKLF

UniProt

Q13351

Swiss Prot

Q13351

Reactivity

Human; Rat; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human KLF1 around the non-acetylation site of Lys274. AA range:231-280

Target

EKLF

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Buffer

-20°C/1 year

Molecular Weight

38kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

38kD

Fragment

IgG

Subcellular Location

Nucleus . Colocalizes with SUMO1 in nuclear speckles. .

Other Product Names

KLF1; EKLF; Krueppel-like factor 1; Erythroid krueppel-like transcription factor; EKLF

Gene ID (Human)

10661

Available Sizes

Frequently Asked Questions

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