EKLF rabbit pAb
This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In (Lu) blood phenotype. [provided by RefSeq, Oct 2009],
Product Specifications
Background
Product Name Alternative
KLF1; EKLF; Krueppel-like factor 1; Erythroid krueppel-like transcription factor; EKLF
UniProt
Q13351
Swiss Prot
Q13351
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human KLF1 around the non-acetylation site of Lys274. AA range:231-280
Target
EKLF
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
38kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
38kD
Fragment
IgG
Subcellular Location
Nucleus . Colocalizes with SUMO1 in nuclear speckles. .
Other Product Names
KLF1; EKLF; Krueppel-like factor 1; Erythroid krueppel-like transcription factor; EKLF
Gene ID (Human)
10661
Available Sizes
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