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DRA rabbit pAb

The protein encoded by this gene is a transmembrane glycoprotein that transports chloride ions across the cell membrane in exchange for bicarbonate ions. It is localized to the mucosa of the lower intestinal tract, particularly to the apical membrane of columnar epithelium and some goblet cells. The protein is essential for intestinal chloride absorption, and mutations in this gene have been associated with congenital chloride diarrhea. [provided by RefSeq, Oct 2008],

Product Specifications

Background

The protein encoded by this gene is a transmembrane glycoprotein that transports chloride ions across the cell membrane in exchange for bicarbonate ions. It is localized to the mucosa of the lower intestinal tract, particularly to the apical membrane of columnar epithelium and some goblet cells. The protein is essential for intestinal chloride absorption, and mutations in this gene have been associated with congenital chloride diarrhea. [provided by RefSeq, Oct 2008]

Product Name Alternative

SLC26A3; DRA; Chloride anion exchanger; Down-regulated in adenoma; Protein DRA; Solute carrier family 26 member 3

UniProt

P40879

Swiss Prot

P40879

Reactivity

Human; Mouse; Rat

Immunogen

Synthesized peptide derived from the C-terminal region of human DRA.

Target

DRA

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Buffer

-20°C/1 year

Molecular Weight

84kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

84kD

Fragment

IgG

Subcellular Location

Apical cell membrane ; Multi-pass membrane protein . Membrane ; Multi-pass membrane protein . Localized in sperm membranes. Midpiece of sperm tail. Colocalizes with CFTR at the midpiece of sperm tail (By similarity) . .

Other Product Names

SLC26A3; DRA; Chloride anion exchanger; Down-regulated in adenoma; Protein DRA; Solute carrier family 26 member 3

Gene ID (Human)

1811

Available Sizes

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