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DNAM-1 rabbit pAb

This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015],

Product Specifications

Background

This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]

Product Name Alternative

CD226; DNAM1; CD226 antigen; DNAX accessory molecule 1; DNAM-1; CD226

UniProt

Q15762

Swiss Prot

Q15762

Reactivity

Human; Rat; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from the Internal region of human CD226. AA range:71-120

Target

DNAM-1

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Buffer

-20°C/1 year

Molecular Weight

38kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

38kD

Fragment

IgG

Subcellular Location

Cell membrane ; Single-pass type I membrane protein .

Other Product Names

CD226; DNAM1; CD226 antigen; DNAX accessory molecule 1; DNAM-1; CD226

Gene ID (Human)

10666

Available Sizes

Curated Selection

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