Macroglobulin α-2 rabbit pAb
Alpha-2-macroglobulin is a protease inhibitor and Cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Product Name Alternative
A2M; CPAMD5; FWP007; Alpha-2-macroglobulin; Alpha-2-M; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5
UniProt
P01023
Swiss Prot
P01023
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human A2M. AA range:871-920
Target
Macroglobulin α-2
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
170kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
170kD
Fragment
IgG
Subcellular Location
Secreted .
Other Product Names
A2M; CPAMD5; FWP007; Alpha-2-macroglobulin; Alpha-2-M; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5
Gene ID (Human)
2
Available Sizes
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