NTE rabbit pAb
This gene encodes a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The protein is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009],
Product Specifications
Background
Product Name Alternative
PNPLA6; NTE; Neuropathy target esterase; Patatin-like phospholipase domain-containing protein 6
UniProt
Q8IY17
Swiss Prot
Q8IY17
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human PNPLA6. AA range:1031-1080
Target
NTE
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
150kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
150kD
Fragment
IgG
Subcellular Location
Endoplasmic reticulum membrane ; Single-pass type III membrane protein .
Other Product Names
PNPLA6; NTE; Neuropathy target esterase; Patatin-like phospholipase domain-containing protein 6
Gene ID (Human)
10908
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
