Fractalkine rabbit pAb
Function: The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium. Binds to CX3CR1. induction: By TNF and IL-1 in pulmonary endothelial cells and umbilical vein endothelial cells. online information: CX3CL1 entry, PTM: A soluble short 95 kDa form may be released by proteolytic cleavage from the long membrane-anchored form. similarity: Belongs to the intercrine delta family. subunit: Monomer. tissue specificity: Small intestine, colon, testis, prostate, heart, brain, lung, skeletal muscle, kidney and pancreas.
Product Specifications
Background
Synonyms
CX3CL1; FKN; NTT; SCYD1; A-152E5.2; Fractalkine; C-X3-C motif chemokine 1; CX3C membrane-anchored chemokine; Neurotactin; Small-inducible cytokine D1
Gene ID
6376
UniProt
P78423
Cellular Locus
Cell membrane ; Single-pass type I membrane protein.; [Processed fractalkine]: Secreted.
Host
Rabbit
Species Reactivity
Human,Rat,Mouse,
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human CX3CL1. AA range:231-280
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC, IF, ELISA
Validated Applications
WB,IHC,IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Molecular Weight
42kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES4084-1.pdf
Observed Molecular Weight
42 kD
Subcellular Location
Cell membrane ; Single-pass type I membrane protein .; [Processed fractalkine]: Secreted .
Other Product Names
CX3CL1; FKN; NTT; SCYD1; A-152E5.2; Fractalkine; C-X3-C motif chemokine 1; CX3C membrane-anchored chemokine; Neurotactin; Small-inducible cytokine D1
Gene ID (Human)
6376
SwissProt (Human)
P78423
Available Sizes
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