Fractalkine rabbit pAb

Function: The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium. Binds to CX3CR1. induction: By TNF and IL-1 in pulmonary endothelial cells and umbilical vein endothelial cells. online information: CX3CL1 entry, PTM: A soluble short 95 kDa form may be released by proteolytic cleavage from the long membrane-anchored form. similarity: Belongs to the intercrine delta family. subunit: Monomer. tissue specificity: Small intestine, colon, testis, prostate, heart, brain, lung, skeletal muscle, kidney and pancreas.