NUMB rabbit pAb
The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016],
Product Specifications
Background
Synonyms
NUMB; Protein numb homolog; h-Numb; Protein S171
Gene ID
8650
UniProt
P49757
Cellular Locus
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from the Internal region of human NUMB.
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IF, ELISA
Validated Applications
WB,IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:500-2000; IF/ICC 1:100-500; ELISA 1:5000-20000
Molecular Weight
70kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES4050-1.pdf
Observed Molecular Weight
70 kD
Subcellular Location
Other Product Names
NUMB; Protein numb homolog; h-Numb; Protein S171
Gene ID (Human)
8650
SwissProt (Human)
P49757
Available Sizes
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