MACC1 rabbit pAb
MACC1 is a key regulator of the hepatocyte growth factor (HGF; MIM 142409)-HGF receptor (HGFR, or MET; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al. 2009 [PubMed 19098908]). [supplied by OMIM, Mar 2009],
Product Specifications
Background
Product Name Alternative
MACC1; Metastasis-associated in colon cancer protein 1; SH3 domain-containing protein 7a5
UniProt
Q6ZN28
Swiss Prot
Q6ZN28
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human MACC1. AA range:411-460
Target
MACC1
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
97kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
97kD
Fragment
IgG
Subcellular Location
Cytoplasm . Nucleus . Mainly found in the cytoplasm in non-metastasizing tumors.
Other Product Names
MACC1; Metastasis-associated in colon cancer protein 1; SH3 domain-containing protein 7a5
Gene ID (Human)
346389
Available Sizes
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