Nectin 3 rabbit pAb
This gene encodes a member of the nectin family of proteins, which function as adhesion molecules at adherens junctions. This family member interacts with other nectin-like proteins and with afadin, a filamentous actin-binding protein involved in the regulation of directional motility, cell proliferation and survival. This gene plays a role in ocular development involving the ciliary body. Mutations in this gene are believed to result in congenital ocular defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011],
Product Specifications
Background
Synonyms
PVRL3; PRR3; Poliovirus receptor-related protein 3; CDw113; Nectin-3; CD113
Gene ID
25945
UniProt
Q9NQS3
Cellular Locus
Cell membrane ; Single-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human PVRL3. AA range:311-360
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA
Validated Applications
WB,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Molecular Weight
60kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES3991-1.pdf
Observed Molecular Weight
60 kD
Subcellular Location
Cell membrane ; Single-pass membrane protein . Cell junction, synapse, postsynaptic cell membrane .
Other Product Names
PVRL3; PRR3; Poliovirus receptor-related protein 3; CDw113; Nectin-3; CD113
Gene ID (Human)
25945
SwissProt (Human)
Q9NQS3
Available Sizes
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