CYP11B1/2 rabbit pAb
Cytochrome P450 family 11 subfamily B member 1 (CYP11B1) Homo sapiens This gene encodes a member of the Cytochrome P450 superfamily of enzymes. The Cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Product Name Alternative
UniProt
P15538
Swiss Prot
P15538
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from the N-terminal region of human CYP11B1/2. AA range:61-110
Target
CYP11B1/2
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
58kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
58kD
Fragment
IgG
Subcellular Location
Mitochondrion inner membrane ; Peripheral membrane protein .
Other Product Names
Gene ID (Human)
1584
Available Sizes
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