Cytokeratin 14 rabbit pAb
This gene encodes a member of the keratin family, the most diverse group of intermediate filaments. This gene product, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12-p11. [provided by RefSeq, Jul 2008],
Product Specifications
Background
UniProt
P02533
Swiss Prot
P02533
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from the C-terminal region of human KRT14. AA range:421-470
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
Molecular Weight
53kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
53kD
Fragment
IgG
Subcellular Location
Cytoplasm. Nucleus. Expressed in both as a filamentous pattern.
Other Product Names
KRT14; Keratin, type I cytoskeletal 14; Cytokeratin-14; CK-14; Keratin-14; K14
Gene ID (Human)
3861
Available Sizes
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